Personal Genome Project

Research articles which use tissues from PGP participants

2009

Ball MP, Li JB, Gao Y, Lee J, LeProust E, Park I-H, Xie B, Daley GQ, Church GM. Targeted and whole-genome methylomics reveals gene-body signatures in human cell lines. Nature Biotechnol 27:361-8. (PDF)

Li JB, Gao Y, Aach J, Zhang K, Kryukov GV, Xie B, Ahlford A, Yoon J-K, Rosenbaum AM, Zaranek AW, LeProust E, Sunyaev SR, Church GM. Multiplex padlock capturing and sequencing reveal human hypermutable CpG variations. Genome Res 19(9):1606-15. (PDF)

Zhang K, Li JB, Gao Y, Egli D, Xie B, Lee JH, Aach J, LeProust E, Eggan K, Church GM (20-Jul-2009) Digital RNA Allelotyping Reveals Tissue-specific and Allele-specific Gene Expression in Human. Nature Methods 6, 613 - 618. (abstract)

Sommer MO, Dantas G, Church GM. Functional characterization of the antibiotic resistance reservoir in the human microflora. Science. 2009 Aug 28;325(5944):1128-31. (PDF)

Sullivan GJ, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross J, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, Iredale JP, Wilmut I (2009) Generation of Functional Human Hepatic Endoderm from Human iPS cells (Hepatology in press)

Lee J, Park IH, Gao Y, Li JB, Li Z, Daley G, Zhang K, Church GM (2009) Changes in Allele-specific Gene Expression In Human Induced Pluripotent Stem Cells (submitted to Nature Genetics)

Thakuria JV, Wu X, Zaranek AW, Rosenbaum AM, Li J, Hulick P, Murray M, Browning MF, Rienhoff HY, Cox G , Rehm H, Berry G , Church GM (2009) Clinical interpretation of variants in individual human genomes (in revision)

Drmanac et al. (2009) Efficient sequencing of human genomes using unchained base reading on self-assembling DNA nanoarrays, (in preparation, for submission to Science).